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However, recent studies have shown their potential in weight management, leading to the development of medications specifically aimed at weight loss, such as Wegovy
This positions retatrutide results favorably for long-duration preclinical study designs
Why this matters: - Hypertension remains the #1 modifiable risk factor for early death globally
Subsequent trials, including SUSTAIN-6, Harmony Outcomes, and AMPLITUDE-O, reported similar MACE reductions but without a mortality benefit [15,16,17]
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